A Study to Compare the Socio Demographic Profile and Causes of Death Between Wave 1 and Wave 2 of COVID 19 Deaths at NRS Medical College, Kolkata

Authors

  • S Chattopadhyay Professor,Dept of FMT, N.R.S Medical College, Kolkata.
  • S S Dutta Associate Professor, Dept of FMT, N.R.S Medical College, Kolkata.
  • S Adhikary Senior Resident,Dept of FMT, N.R.S Medical College, Kolkata.

DOI:

https://doi.org/10.48165/jiafm.2023.45.4.10

Keywords:

COVID-19, Wave l, Wave 2, Acute Respiratory Infection, Pneumonia

Abstract

The COVID 19 pandemic has spread across the globe since December 2019. Its surge in three phases in India has been phenomenal.  Mortality was more in the first and second waves. The present study is a descriptive study with an attempt to identify the mortality data in  the 2 waves (W) – W1 extending from April 2020 to February 2021 and W2 from March 2021 to June 2021 at NRS Medical College,  Kolkata. All SARS-CoV-2 positive cases that died in the hospital after admission or were brought dead at the hospital during the defined  period were included in the study. Mortality among males was more than females in both the waves. In W1, individuals in the age group of  61-70 years were the most vulnerable whereas in W2 it was 51-60 years. However the cumulative mortality in the age group of 41-60 years  increased from 33.7% in W1 to 41.8% in W2. The 4 to 14 days survival period after hospital admission increased from 34.3% in the first  wave to 43.3% in the subsequent wave. Severe Acute Respiratory Infection was documented as the commonest cause of death in W1 and  Pneumonia in W2. Nearly 60% of the deceased of W1 and 46.7% in W2 had comorbidities. Diabetes and hypertension were found to be the  commonest comorbidities associated with fatality. 

Downloads

Download data is not yet available.

References

Centers for disease control and prevention. Principles of Epidemiology in Public Health Practice: An Introduction to Applied Epidemiology and Biostatistics [Internet]. Atlanta: U.S. Department of Health and Human Services; 2006 Oct [Updated 2012 May; cited 2021 June 10]. Available from: https://www.cdc.gov/csels/dsepd/ss1978/ss1978.pdf.

Guo YR, Cao QD, Hong ZS, Tan YY, Chen SD, Jin HJ et al. The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak: An update on the status. Mil. Med. Res. 2020;7:1–10. doi: 10.1186/s 40779-020-00240-0.

Li Q, Guan X, Wu P, Wang X, Zhou L, Tong Y et al. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. N. Engl. J. Med. 2020;382:1199–1207. doi: 10.1056/NEJMoa2001316.

Andrews MA, Binu A, Rajesh KR, Krishnan J, Suryakala R, Krishnan B et al. First confirmed case of COVID- 19 infection in India: Acase report. Indian J Med Res. 2020 May; 151(5): 490–492. doi: 10.4103/ ijmr.IJMR_2131_20

Ahmad FB, Anderson RN. The leading causes of death in the US for 2020. JAMA. 2021;325(18):1829-1830. doi:10.1001 /jama.2021.5469

Singh J, Rahaman SA, Ehtesham NZ, Hira S, Hasnain SE. SARS-CoV-2 variants of concern are emerging in India. Nat Med. 2021; 27: 1131-33.

Dhar MS, Marwal R, Radhakrishnan VS et al. Genomic characterization and Epidemiology of an emerging SARS –CoV-2 variant in Delhi, India. Science 2021 Nov; 374 (6570): 995-999. doi:10.1126/science.abj9932

Yang X, Yu Y, Xu J, Shu H, Xia J, Liu H, et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: A single-centered, retrospective, observational study. Lancet Respir. Med. 2020;8:475–481. doi: 10.1016/S2213-2600(20)30079-5.

Mohan A, Tiwari P, Bhatnagar S, et al. Clinico-demographic profile & hospital outcomes of COVID-19 patients admitted at a tertiary care centre in north India. Indian J Med Res. 2020;152(1,2): 61-69. doi: 10.4103/ijmr.IJMR_1788_20.

Towhig KA, Nyberg T, Zaidi A et al. Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variant of

concern: a cohort study. Lancet Infect Dis. 2022; 22:35-42.

Chen T, Wu D, Chen H, Yan W, Yang D, Chen G, et al. Clinical characteristics of 113 deceased patients with coronavirus disease 2019: Retrospective study. BMJ. 2020;368:m1091. doi: 10.1136 /bmj.m1091.

Dudley JP, Lee NT. Disparities in age-specific morbidity and mortality from SARS-CoV-2 in China and the Republic of Korea. Clin. Infect. Dis. 2020;71:863–865. doi: 10.1093/cid/ciaa354.

Borghesi A, Zigliani A, Masciullo R, Golemi S, Maculotti P, Farina D, et al. Radiographic severity index in COVID-19 pneumonia: Relationship to age and sex in 783 Italian patients. Radiol. Med. 2020;125:461–464. doi: 10.1007/s11547-020-01202-1.

Asirvatham ES, Sarman CJ, Sarvanamurthy SP, et al. Who is dying from COVID-19 and when? An Analysis of fatalities in Tamil Nadu, India. Clin Epidemiol Glob Health. Jan-Mar 2021; 9: 275-279. doi: 10.1016/j.cegh.2020.09.010.

Contou D, Cally R, Sarfati f, Desaint P, Fraisse M, Plantefeve G. Causes and timing of death in critically ill COVID-19 patients. Crit Care. 2021; 25:79. doi.10.1186/s13054-021- 03492-x

Elezkurtaj S, Greuel S, Ihlow J etal. Causes of death and comorbidities in hospitalized patients with COVID-19. Sci Rep. 2021 Feb 19; 11(1): 4263. doi: 10.1038/s41598-021- 82862-5.

Slater TA, Straw S, Drozd M, Kamalathasan S, Cowley A, Witte KK. Dying 'due to' or 'with' COVID-19; a cuase of death analysis in hospitalized patients. Clinical Medicine. Sept 2020. 20:5. doi:10.7861/clinmed.2020-0440.

Published

2023-12-25

How to Cite

Chattopadhyay, S., Dutta , S. S., & Adhikary , S. (2023). A Study to Compare the Socio Demographic Profile and Causes of Death Between Wave 1 and Wave 2 of COVID 19 Deaths at NRS Medical College, Kolkata . Journal of Indian Academy of Forensic Medicine, 45(4), 357-360. https://doi.org/10.48165/jiafm.2023.45.4.10