A Comprehensive Retrospective Analysis in Understanding Covid-19 : Forensic Perspective from a Single Institute
DOI:
https://doi.org/10.48165/jiafm.2023.45.4.12Keywords:
Covid-19, Clinical features, Comorbidities, VaccinationAbstract
SARS-CoV-2 has spread swiftly and disseminated as a pandemic globally. As there was limited research on non-autopsy findings, a detailed analysis of facts gathered from the deceased can aid in a better understanding of the covid disease. The current retrospective cross sectional study was conducted on the 388 probable COVID-19 fatalities, in the department of Forensic Medicine and Toxicology, between st August 1 2020 to August 1st, 2021. Deaths were more common in the age group of 41-60 years with male predominance with greater number being in the Prevaccination period. 74% reported cough, 85% shortness of breath, 88% had fever and anosmia in very few cases. Co-morbidities observed were 18% of hypertension, 16% diabetes and 8% chronic renal disease. Common reasons being respiratory failure due to bilateral pneumonia followed by multi-organ failure and cardiac arrest. Comorbidities added to severity and vaccination has shielding effect in the prevention of deaths.
Downloads
References
Arora V, Sharma S, Saini T, Kumar D. Effect of first sixty eight days of lockdown due to COVID-19 on autopsy cases in a tertiary care teaching hospital situated in a rural area of Himachal Pradesh. J Indian Acad Forensic Med. 2021 Oct Dec; 43(4): 363-365. doi:10.5958/0974-0848.2021.00092.0
Kumar B, Kumar A, Singh NP, Gupta RB, Goel N, Singh NK. P. Modern Mortuary Complex Plan in Covid-19 Era. J Indian Acad Forensic Med. 2022 July-Sep. 44 (3) DOI : 10.5958/0974-0848.2022.
Kanchan T, Meshram VP, Shekhawat RS, Misra S. Healthcare workers and COVID-19 pandemic: A fight amidst fear of burnout. J Indian Acad Forensic Med. 2020 Jul-Sep; 42(3): 153-154. doi:10.5958/0974- 0848.2020.00042.1
Arora V, Sharma S, Saini T, Kumar D. Effect of first sixty eight days of lockdown due to COVID-19 on autopsy cases in a tertiary care teaching hospital situated in a rural area of Himachal Pradesh.J Indian Acad Forensic Med. 2021 Oct Dec; 43(4): 363-365. doi:10.5958/0974-0848.2021.00092.0
WHO. 2020. Coronavirus Disease (COVID-19) Situation Reports. [Cited 11th Apr 2022]. Available from: https:// www.who.int/emergencies/diseases/novel-coronavirus 2019/situation-reports
WHO Coronavirus (COVID-19) Dashboard. [Cited 15th Apr 2022]. Available from: https://covid19. who.int/.
Economic and Social Council, United Nations, in Progress towards the Sustainable Development Goals. (2022) [Cited 15th Apr 2022]. Available from: https://www.un.org/ sustainabledevelopment/progress- report/
Ministry of health and family welfare. [Cited 30th May 2022]. Available from: https://www. mohfw.gov.in/#
Transition from pandemic. Nat Sustain [Internet]. 2020 May 1;3(5):345–345. Available from: https://doi.org/10.1038 /s41893-020-0546-1.
Patel AP, Vaghela RD, Trivedi JM, Madhavi AR. Profile of medico-legal autopsy cases performed during COVID-19 pandemic lockdown at mortuary of Civil Hospital and B. J. Medical College in Ahmedabad, Gujarat. J Indian Acad Forensic Med. 2021 Jul-Sep; 43(3): 227-231. doi:10.5958/ 0974-0848.2021.00057.9
Sumner A, Hoy C & Ortiz-Juarez E. Estimates of the Impact of COVID-19 on Global Poverty. UNU-WIDER, April 800–9. https://doi. org/ 10. 35188/ UNU- WIDER/ 2020/ 800-9 (2020).
Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a
descriptive study. Lancet. 2020; 395:507-13. https://doi.org/ 10.1016/ So140-6736(20) 30211-7.
Kankar A. COVID-19: The current case fatality rateglobally. [Cited 6th Jun.2020]. Available from: https:// www.biospectrumasia.com/news/83/15738/covid-19-the current- case-fatality-rate-globally-.html.
Slater TA, Sam S, A Michael Drozd, Stephe Kamalathasan, Alice Cowley and Klaus K Witte.Dying 'due to' or 'with' COVID-19: a cause of death analysis in hospitalised patients.Clinical Medicine 2020 Vol 20, No 5: e189–90.
Daily COVID-19 vaccine doses administered India. [Cited 06-11- 2021]. Available from: https://www.mygov. in/covid-19.
Nigam M, Nigam R, Singh RK, Khan MS. Clinico demographic profile of covid 19 mortality in a tertiary care centre of Madhya Pradesh. J Indian Acad Forensic Med. 2022 Jan; 44 (Suppl): S16-S18 doi: 10.5958/0974-0848.2022. 00005
Protocol for COVID-Management Updated Version 2.1 – AIIMS 3rd May 2021. [Cited 13 December 2021]. Available from: https://police.py.gov.in/AIIMS/2003.05.21.pdf.
Butowt R, & von Bartheld CS (2021). Anosmia in COVID-19: Underlying Mechanisms and Assessment of an Olfactory Route to Brain Infection. The Neuroscientist,
(6), 582- 603. Available from: https://doi.org/ 10.1177/1073858420956905.
Meng X, Deng Y, Dai Z, & Meng Z (2020). COVID-19 and anosmia: A review based on up-to-date knowledge. American Journal of Otolaryngology, 41(5), 102581. https://doi.org/10.1016/j.amjoto.2020.102581.
Ramachandran P, Onukogu I, Ghanta S, Gajendran M, Perisetti A, Goyal H, et al. Gastrointestinal symptoms and outcomes in hospitalized coronavirus disease 2019 patients. Dig Dis. 2020;38:373–9.
Wu Y, Xu X, Chen Z, Duan J, Hashimoto K, Yang L, et al. Nervous system involvement after infection with COVID-19 and other coronaviruses. Brain Behav Immun. 2020; 87:18- 22. https://doi.org/10.1016/j.bbi.2020.03.031.
Mao L, Jin H, Wang M, Hu Y, Chen S, He Q, et al. Neurologic Manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China. JAMANeurol. 2020;77:683.
Shahbazi F, Solgi M, Khazaei S. Predisposing risk factors for COVID-19 infection: A case- control study. Caspian J Intern Med 2020; 11(Suppl 1): S495-500.
Zhang JJ, Dong X, Liu GH. et al. Risk and Protective Factors for COVID-19 Morbidity, Severity, and Mortality. Clinic Rev Allerg Immunol (2022). https://doi.org/10.10 07/s12016- 022-08921-5.