Death Due To 2, 4-DI-Ethyl Ester Poisoning –A Rarely Documented Compound in Clinical and Forensic Practice

Authors

  • T Saini Medical Officer (Forensic Medicine Specialist), Civil Hospital, Nurpur, Dist. Kangra.
  • V Arora Professor Department of Forensic Medicine and Toxicology, Dr. Rajendra Prasad Government Medical College, Kangra at Tanda.

DOI:

https://doi.org/10.48165/jiafm.2024.46.1.24

Keywords:

2, 4 Di Ethyl Ester, Herbicide, Phenoxy acetic group

Abstract

Poisoning with Herbicides, Pesticides and Rodenticides etc. is very common nowadays especially in the northern parts of India due to their  easy availability from market. Such compounds are available in the houses of farmers, persons dealing in agriculture sectors. Most of the  time the cases of poisoning which are brought to our hospitals or are brought for autopsy in the mortuaries are of Organo phosphates,  Organo chloro compounds or Aluminum Phosphide poisoning. In this case, we will discuss about the poisoning with a rarely documented  compound 2, 4 Di Ethyl Ester which is a compound of Phenoxy acetic group. 2,4 Dichlorophenoxyacetic acid (2,4-D) is a selective  herbicide used to kill broad leafed plants. The signs and symptoms of this compound mimics with anti-cholinesterase compounds which  might be the reason for under reporting of this compound as a potential cause of poisoning. The role of preserving blood sample during  post-mortem to look for myoglobin and creatine phsphokinase levels may be of help in giving opinion regarding cause of death in case of  negative FSL's reports.  

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References

Pillay VV, A textbook of Modern Medical Toxicology.4th ed, New Delhi: CBS Publishers and Distributors;2013. p.398- 401.

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Keller T, Skopp G, Wu M, Aderjan R: Fatal overdose of 2,4- dichlorophenoxyacetic acid (2,4-D): Forensic Sci Int. 1994;65:13–8.

Jearath V, Negi R, Chauhan V, Sharma K: Arare survival after 2,4-D (ethyl ester) poisoning: Role of forced alkaline dieresis: Indian Journal of Critical care Medicine.2015; 19 (1), 57-8.

S Singh et al: Fatal 2,4-D (Ethyl Ester) Ingestion: J Assoc Physicians India.2003;51,609-10.

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Published

2024-04-23

How to Cite

Saini, T., & Arora, V. (2024). Death Due To 2, 4-DI-Ethyl Ester Poisoning –A Rarely Documented Compound in Clinical and Forensic Practice . Journal of Indian Academy of Forensic Medicine, 46(1), 97-98. https://doi.org/10.48165/jiafm.2024.46.1.24