Gross and Histopathological Changes in Fatal Poisoning
DOI:
https://doi.org/10.48165/Keywords:
Poisoning, Autopsy, Histopathological changes, Intoxication, CynosisAbstract
Prospective two year study period, from 1st August, 2008 to 31st July, 2010, a total of 1,374 autopsies were performed at the centre, 70 cases were suspected cases or confirmed poisoning & those persons declared dead on arrival in the causality and suspected to be a case of poisoning. Incidence of deaths due to poisoning was 5.09 %. Insecticide was commonest poison (22 or 31.42%),followed by alcohol intoxication 16(22.85%). Maximum deaths were due to cerebral edema 18(30.50%) cases. Cyanosis was present in maximum number (24 or 34.28%) of cases. On gross examination, Stomach mucosa was congested in maximum number or 36(51.42%) cases. Sub mucosal hemorrhages in stomach were commonly seen in (12 cases) insecticide poisonings. On histopathological examination, in liver, fatty changes were seen in maximum number of (13 or 59.09%) cases followed by ballooning degeneration in 3(13.63%) cases. In kidneys, cloudy degeneration was seen in maximum (12 or 54.54%) cases followed by acute tubular necrosis in 8(36.36%) cases.
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References
Karmakar RN editor. JB Mukherjee’s Forensic Medicine and
Toxicology. 3rd ed. Kolkata Academic Publishers 2007:1051.
Sepha GC, Bharani AK, Jain SM, Raman PC. Acute aluminium
phosphide poisoning. J Indian Med Assoc. 1989; 83: 378-79.
Khurram SR, Fazal MO, Bilal A, Qurashi FS, Muqqadas S.
Organophosphorus compound poisoning; epidemiology and
management. Prof J of med. 2008; 15(4):518-523.
Aggarwal NK, Aggarwal BBL. Trends of poisoning in Delhi. J
Indian Acad of Forensic Med.1998; 20:33-36.
Kiran N, Shobha Rani RH, Jaiprakash V, Vanaja K. Pattern of
poisoning reported at south Indian tertiary care hospital. Indian J of
Forensic Med & Toxicology. 2008; 2:17-19.
Gupta BD, Vahela PC. Profile of fetal poisoning in and around
Jamnagar. J of Indian Acad. of Forensic Med.2005; 27:145-148.
Dalal JS, Goria RK, Aggarwal KK, Thind AS, Sandhu SS.
Poisoning trends- A post-mortem study. J of Indian Acad. of
Forensic Med.1998; 20:27-36.
Reddy K.S.N. The essentials of Forensic Medicine and Toxicology
th Ed 2008:437-567.
Sutay SS, Tirpude BH. Pattern of histopathological changes of
liver in poisoning. J of Indian Acad. of Forensic Med.2008; 30:63-
Gupta SK, Kumar S, Sheikh MI. Study of Organophosphorus
poisoning in Surat, India. J of Indian Acad. of Forensic Med. 2006;
:83-87.
