Stem Cells: An Update
DOI:
https://doi.org/10.48165/Keywords:
Stem cells, Embryonic stem cells, Adult stem cells, Mesenchymal stem cellsAbstract
Stem cells are unspecialized cell. They are capable of continuous self-renewal. They can give rise to specialized cell types. Since the discovery of stem cells till now, for years scientists have been working on the numerous possibilities that the stem cells have and studies carried out to channelize their sources to the best for benefit of mankind. Starting from the knowledge of only embryonic stem cells as the source of stem cells, now it is known that they can be extracted from cord blood and mature adult tissue. Likewise, their applications earlier limited to restoration of diseased and damaged tissue or organs have also found their place in Forensic science investigations as well. More recently use of stem cells have been found to be useful in the research arena allowing the scientists to develop models for studying human biology, pathology and genetics. This article is a general update on stem cells, their properties, sources and current applications in Medicine.
Downloads
References
Bongso A and Lee E H. Stem Cells: Their Definition, Classification and Sources. In: Stem Cells: from bench to bedside World Scientific; Singapore: 2005. p. 1-13.
Karien GA. Dental Pulp Stem Cells, a New Era in Tissue Engineering. Smile Dental Journal 2009; 4:6-9.
Understanding stem cells-an overview of the science and issues from the National Academies [WWW] : The National Academies c2005–[cited 2005] Available from: http://dels old.nas.edu/dels/rpt_briefs/Understanding_Stem_Cells.pdf
Dias TP, Machado Maria Aparecidade Andrade Moreira, Thiemy SV, Eduardo N J. Pulp tissue from primary teeth: new source of stem cells. J. Appl. Oral Sci 2011; 19:189-94.
Torrisi CP. Embryonic vs. Adult: The History and Future of the Stem Cell Debate J. Health & Biomedical L 2007;111: 143-62. 6. Bluteau G, Luder HU, De Bari C, Mitsiadis T A. Stem cells for tooth engineering. Eur cell Mater 2008; 16:1-9.
Egusa H, Sonoyama W, Nishimura M, Atsuta I, Akiyama K. Stem cells in dentistry– Part I: Stem cell sources. J Prosthodont Res2012; 56:151–65.
Dias TP, Machado MAAM, Sakai VT, Nör J E. Pulp tissue from primary teeth: new source of stem cells. J Appl Oral Sci 2011; 19:189-94.
Stem cell research & therapy: types of stem cells and their current uses. In Stem cell [WWW] UK: Stem cells,2012 [cited August 17,2012] Available at: http://www.eurostemcell.org/factsheet/stem cell-research-therapy-types-stem-cells-and-their-current-uses
Mao JJ. Stem cells and future of dental care. N Y State Dent J 2008; 74:20-4.
NIH Stem Cell Information Home Page. In Stem Cell Information [WWW]. Bethesda, MD: National Institutes of Health, U.S. Department of Health and Human Services, 2013 [cited December 26, 2013] Available at: http://stemcells.nih.gov/info/scireport/pages/chapter3.aspx
Biotech articles [WWW]. Uppangala N. Amniotic stem cells and its future applications. Stem cells.c2010.[cited May 21,2010] Available from : http://www.biotecharticles.com/Stem-Cells-Article/Amniotic Stem-Cell-and-Its-Future-Applications-32.html
American Association for the Advancement of Science and Institute for Civil Society [WWW ].Chapman AR, Frankel M S, Garfinkel M S. Stem Cell Research and Applications-Monitoring the Frontiers of Biomedical Research.c1998 [cited November, 1999] Available from: http://www.aaas.org/spp/sfrl/projects/stem/report.pdf
The center for Bioethics and Human Dignity [WWE site]. Riggan K. Cord Blood Stem Cells: An Overview.DignitasCBHDc2009 [cited December16, 2009] Available from : http://cbhd.org/content/cord-blood-stem-cells-overview
The academy of Dental therapeutics and Stomatology[WWW ].Mao JJ, Collins FM. Stem Cells: Sources, Therapies and the Dental
Professional.2011 [cited November,2012] Available from : http://www.ineedce.com/courses/1486/PDF/StemCells.pdf 16. Abdallah BM, Kassem M. Human mesenchymal stem cells: from basic biology to clinical applications. Gene Therapy 2008; 15:109– 16.
Bajada S, Mazakova I, Richardson JB and Ashammakhi N. Updates on stem cells and their applications in regenerative medicine. J Tissue Eng Regen Med 2008; 2:169–83.
Mimeault M, Hauke R, Batra SK. Stem cells: a revolution in therapeutics-recent advances in stem cell biology and their
therapeutic applications in regenerative medicine and cancer therapies. Clinc. Pharmacol. Ther 2007; 82: 252–264.
Pretty A, Sweet D. A look at forensic dentistry —Part 1: The role of teeth in the determination of human identity. Brit Dent J 2001;190: 359-65
ICMR-DBT Guidelines for stem cell research and therapy 2007 http://icmr.nic.in/stem_cell_guidelines.pdf
Moharamzadeh K, Brook IM, Noort RV,Scutt AM,Thornhill MH. Tissue-engineered Oral Mucosa: a Review of the Scientific Literature. J Dent Res2007; 86:115-124.
