Mercury Poisoning: Analytical Aspects with Brief Overview
DOI:
https://doi.org/10.48165/Keywords:
Mercury, Toxicity, Analysis, Immune system, Nervous systemAbstract
Mercury (quicksilver) comes under the class of metallic poisons. At room temperature the metal is in liquid form. Although metallic mercury is not poisonous, but it causes poisoning when inhaled in its vapour form, swallowed or rubbed into skin. The toxicity of mercury depends on its chemical form and route of exposure. It affects the immune system, alters genetic and enzyme systems, and damages the nervous system, including incoordination and the tactile, gustatory and visual hallucinations. Clinical features of mercury poisoning along with differential diagnosis have been presented. The pre-hospital, hospital and post-hospital management will help in providing the proper care to the patient along with the treatment which can be done using BAL, DMSA etc. The qualitative as well as quantitative determination of mercury levels can be done with the help of various sophisticated techniques.
Downloads
References
Brown, S.S. (ed), Clinical Chemistry and Chemical Toxicology of Metals, Elsevier, North Holland, 1977; 308
http://www.epa.gov/hg/about.htm accessed on 20/02/2014 3. http://www.ehs.okstate.edu/training/mercury.htm accessed on 21/02/2014
http://www.lenntech.com/periodic/elements/hg.htm#ixzz0wVhsqtbc accessed on 28/02/2014
http://labmed.ascpjournals.org/content/33/8/614.full.pdf accessed on 28/02/2014
http://www.usgs.gov/themes/factsheet/146-00/ accessed on 28/02/2014
Lyon’s Medical Jurisprudence & Toxicology (11thEdn) Delhi Law House Publishing Co. Ltd, New Delhi 2005, 1155
Mathiharan K, Kannan K. editor. Modi A Textbook of Medical Jurisprudence and Toxicology. 23th ed. Nagpur: LexisNexis Butterworth’s Wadhwa; 2005 p139.
http://emedicine.medscape.com/article/1175560-overview accessed on 15/2/2014
Parikh C. K. Text book of Medical Jurisprudence, Forensic Medicine and Toxicology, 2012; 6th Ed, CBS Publishers and distributors,New Delhi 2005 p9-15.
Reddy K. S. Narayan. The Essentials of Forensic Medicine and Toxicolgy.2005; 29th edition:555
Sharma, B.R. Forensic Science in Criminal Investigation and Trials (3rdEdn) Universal Law Publishing Co. Ltd, New Delhi, 2001, 782
DFS Manual of Toxicology.1stEdn. Selective & Scientific Publisher, New Delhi, 2005:94-99.
Tiwari SN. Manual of Toxicology Forensic Science Laboratory, Agra 1stEdn.1976: 58
Vogel, A.I. A Text Book of Macro and Semi Micro Qualitative Inorganic Analysis, 4thEdn. Longman, London, 1964.
Skoog. Fundamental of Analytical Chemistry, 8thEd.Thomsan/Brook/Cole, Page 710.
Evans SJ, Johnson MS, Leah RT. Determination of Mercury in Fish Tissue, a Rapid, Automated Technique for Routine Analysis, Application Note by Agilent Technologies,2010.[www.agilent.com/chem] assessed on 01/03/2014
X. Han Fengxiang, Patterson WD, Xia Yunju, Sridhar BB Maruthi, Su Yi. Rapid determination of mercury in plant and soil samples by using ICP-AES a comparative study. Water, Air and Soil Pollution. 2006, 170(1-4); 161-171.
Bettinelli M, Beone GM, Spezia S, Baffi C. Determination of heavy metals in solids and sediments by microwave-assisted digestion and inductively coupled plasma-optical emission spectrometry analysis. Analytica. Chimica. Acta. 2000, 424(2):289-296.
Nixon DE, Burritt MF, Moyer TP. Determination of Mercury in Whole Blood and Urine by Inductively Coupled Plasma –Mass Spectrometry. SpectrochimicaActa Part B,1999;54: 1141-1153
www.prenhall.com/settle/chapters/ch37.pdf accessed on 23/03/2014.
Application Bulletin 96/5 e by Metrohm.
www.laboratory-journal.com accessed on 15/03/2014 24. Rook HL, Gills TE, Lafleur PD. Method for Determination of Mercury in Biological Materials by Neutron Activation Analysis. Analytical Chemistry 1972,44(7);1114-1117
http://emedicine.medscape.com/article/1175560-treatment accessed on 26/9/2013
Cahide Yilmaz, Mesut Okur, Hadi Geylani, Hüseyin Çaksen, Oğuz Tuncer, Bülent Ataş. Chronic mercury poisoning: Report of two siblings. Indian Journal of Occupational & Environmental Medicine, 2010;14(1):17-19