Disseminated invasive Aspergillosis in a case of fatal antemortem flame burns

Abstract

In the burn patients who survive, the most important factor limiting survival is infections. Today, the survival of a seriously burned  patient is better due to advancements in burn care therapy. However, they still face increased risk of infectious complications, notably  fungal infections. Broad-spectrum antibiotic therapy, large wound surface and impaired immune system contribute to the growth of  opportunistic fungal species. As per available data, though burn wound are mostly contaminated by Candida, the fungal isolate  commonly involved in invasion and dissemination across the body is Aspergillus. We report a case of Disseminated Invasive  Aspergillosis of lung, heart and kidneys in a case of fatal antemortem flame burns in a 36 years old female. This case clearly shows  awareness of possible dissemination of Aspergillus spp. is necessary in patients who have a burn injury, even if the patient has no risk  factors as it is typically associated with a poor prognosis.