Estimation of Redox Marker Carbonyl Compound in Subjects after Death from Various Causes - As an Important Biochemical Parameter to Estimate Time Passed Since Death.

Abstract

Time passed since death is the period that has elapsed between death and the actual performance of postmortem examination. There are lots  of research work undertaken to estimate time passed since death based on biochemical changes of postmortem blood. After death the  defence parameters which protect the human cell to maintain the redox balance alters slowly. Carbonyl compound, reactive intermediates  of glucose degradation pathway generated on auto oxidation of glucose are capable of inducing cellular damage. Changes of redox marker  carbonyl compound in postmortem blood are proportional to the time passed since death. It provides a theoretical basis on which time of  death can be calculated.